Course : MOC Part II: Clinical Molecular Genetics and Genomics Literature Review (Issue 2017)

The Literature Review modules are comprised of 5-8 current and relevant literature articles in this specialty.  The topics encompass new clinical applications or methodologies, diagnostic methods and approaches, management and treatment of genetic conditions, and relevant practice guidelines.  

Diplomates are required to complete one Part II literature review module per 3 year timeframe of their ABMGG Continuing Certification MOC program.

New modules will be posted every two years. Each module will be available for a three-year period of time, so that up to two modules will be available at any given time.

Each literature review module consists of:

  • Optional pre-reading test - Diplomates can take a 25 question pre-test. The score of the pre-test is revealed to the test taker only and a passing score does not exempt the diplomate from taking the post-test.
  • Set of required reading -Full citations for five to eight specialty-specific articles will be listed.
  • Post-reading test - Consists of the same 25 multiple-choice questions as the pre-test. Responses are scored immediately. Diplomates who do not achieve a passing score of 80% may repeat the test until a passing score is attained.

Educational Credits

Date of Release: August 28th, 2017
Expiration Date: December 31, 2020
Estimate Time of Completion: 8 hours
Course must be completed by the expiration dates

Click here for more information about this course.

Registration and Fees

CME Credits and MOC Part II Certificate ($25)
MOC Part II Certificate Only ABMGG Diplomates ($0/no cost)


At the conclusion of this course, participants should be able to:

  1. Explain the role of the PALB gene in the development of breast cancer.
  2. Describe the utility of the specifically-designed TALE-nuclease to correct a 2pb deletion in the XPC gene as a first step toward gene therapy in patients with xeroderma pigmentosum.
  3. Apply the correct nomenclature to apply when reporting sequences variants associated with pharmacogenetic phenotypes and how the nomenclature was developed.
  4. Apply the Chinese menu approach to the interpretation of rare sequence variants.
  5. Review the scope of clinical genetic testing using post-millennium genetic technologies.

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